Anti-ß2 microglobulin (caiman, ß2M)
Mouse monoclonal antibody
Cat.No. KSK 003-01
Preparation: Protein-A/G purified
Content: Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
ß2 microglobulin (ß2M) is a 12-14 kDa subunit of the major histocompatibility complex (MHC) class I. ß2M is a non-polymorphic molecule and is not involved in peptide binding but is essential for MHC assembly. ß2M is also found in free form in the plasma. MHC class I is expressed on most nucleated cells in the caiman, including the red blood cells.
Recombinant caiman ß2M
KSK 003-01 reacts with free as well as MHC class I associated ß2M
Reacts with a non-polymorphic epitope on caiman ß2M
KSK 003-01 is suitable for Western blotting, flow cytometry, immunoprecipitation, and affinity purification on caiman ß2M.
| Method | Usability | References |
| ELISA | Not determined | |
| Immunoblotting | Yes | |
| Immunohistochemistry | Not determined |
1. Kaufman J, Skjoedt K, Salomonsen J (1990) The MHC molecules of nonmammalian vertebrates. Immunol Rev 113:83-117.
2. Kaufman J, Skjoedt K, Salomonsen J, Simonsen M, Pasquier L. Du, Parisot R, Riegert P (1990) MHC-like molecules in some nonmammalian vertebrates can be detected by some cross-reactive xenoantisera. J Immunol 144:2258-2272.
