Anti-Streptolysin

Mouse monoclonal antibody

Cat.No. HAB 003

Subclass IgG1/k
Presentation:

Preparation: Protein-A/G purified
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.

Antigen:

Bacteria of the Streptococcus genera produce the exotoxin streptolysin. Anti-streptolysin antibody titers in patients are measured as a marker of inflammation. Streptolysin is also an important tool in cell biology due to its hemolytic activity and the ability to permeabilize plasma membranes.

Immunogen:

Cysteine chloride reduced streptolysin adsorbed onto aluminum hydrroxide gel

Specificity:

HAB-003 is specific for reduced streptolysin but cross reacts to untreated streptolysin

Epitope specificity:

Not determined

Reactivity:

HAB-003 reacts weakly with cysteine chloride oxidized streptolysin directly coated onto the microtiter plate.

Application:
Method Usability References
ELISA Yes
Immunoblotting Not determined
Immunohistochemistry Not determined

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