Anti-M-Ficolin (human)
Mouse monoclonal antibody
Cat.No. ABS 036-05
Preparation: Protein-A/G purified
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway (1).
Recombinant human M-Ficolin (aa 95 to 314) adsorbed onto aluminum hydroxide gel
ABS 036-05 reacts specifically with M-Ficolin
Not determined
In ELISA ABS 036-05 reacts with recombinant M-Ficolin coated directly into the microtiter well.
| Method | Usability | References |
| ELISA | Yes | |
| Immunoblotting | Not determined | |
| Immunohistochemistry | Not determined |
1. Liu Y, Endo Y, Iwaki D, Nakata M, Matsushita M, Wada I, Inoue K, Munakata M, Fujita T (2005) Human M-Ficolin is a secretory protein that activates the lectin complement pathway. J Immunol 175:3150-3156.
